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ML417

Glpbio
Catalog No:GC39752-10mM (in 1mL DMSO) CAS No.:1386162-69-1 MDLNo: Brand:Glpbio purity: 特性: Purpose:ML417 是一种选择性的,可透过血脑屏障的 D3 多巴胺受体 (D3R) 激动剂,EC50 为 38 nM。ML417 促进 D3R 介导的 β-arrestin 易位、G 蛋白介导的信号传导和 pERK 磷酸化,对其他 GPCR 介导的信号传导影响最小。ML417 对毒素诱导的多巴胺能神经元变性具有神经保护作用。DMSO: 50 mg/mL (131.77 mM)
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